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KMID : 1189320150090060952
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Asian Spine Journal
2015 Volume.9 No. 6 p.952 ~ p.957
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Variety of the Wave Change in Compound Muscle Action Potential in an Animal Model
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Ito Zenya
Imagama Shiro
Ando Kei
Muramoto Akio
Kobayashi Kazuyoshi
Hida Tetsuro
Ito Kenyu
Ishikawa Yoshimoto
Tsushima Mikito
Matsumoto Akiyuki
Tanaka Satoshi
Morozumi Masayoshi
Matsuyama Yukihiro
Ishiguro Naoki
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Abstract
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Study Design: Animal study.
Purpose: To review the present warning point criteria of the compound muscle action potential (CMAP) and investigate new criteria for spinal surgery safety using an animal model.
Overview of Literature: Little is known about correlation palesis and amplitude of spinal cord monitoring.
Methods: After laminectomy of the tenth thoracic spinal lamina, 2-140 g force was delivered to the spinal cord with a tension gage to create a bilateral contusion injury. The study morphology change of the CMAP wave and locomotor scale were evaluated for one month.
Results: Four different types of wave morphology changes were observed: no change, amplitude decrease only, morphology change only, and amplitude and morphology change. Amplitude and morphology changed simultaneously and significantly as the injury force increased (p<0.05) Locomotor scale in the amplitude and morphology group worsened more than the other groups.
Conclusions: Amplitude and morphology change of the CMAP wave exists and could be the key of the alarm point in CMAP.
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KEYWORD
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Compound muscle action potential, Morphology change, Amplitude
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